Science

Enzyme discovery opens a new route to natural UV-absorbing saclipins

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Based on a feed excerpt; full article content has not been acquired. Source evidence retrieved 14/10/2026, 15:55:24 UTC.

Briefings

A new enzyme discovery has identified a pathway for producing saclipins A and B, natural UV-absorbing oxylipins from the cyanobacterium Aphanothece sacrum. These compounds are currently used in Japanese cosmetics but face challenges due to their low natural abundance and complex biosynthesis. The study provides a potential route to enhance their production for broader applications in cosmetics and protective materials.

Key points

• Saclipins A and B are UV-absorbing oxylipins produced by the freshwater cyanobacterium Aphanothece sacrum, known in Japan as Suizenji-nori.
• The discovery of an enzyme that facilitates the biosynthesis of saclipins A and B offers a new route to increase their natural abundance.

Context and limitations

The study focuses on the discovery of an enzyme pathway; specific biosynthetic steps, exact production rates, and long-term efficacy in cosmetic applications remain to be determined.

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